Antibody molecule
نویسندگان
چکیده
منابع مشابه
The Antibody Molecule
With the burgeoning state of research in immunology, it is becoming increasingly difficult to follow the more recent studies in immunochemistry, cellular immunity, and clinical immunology. Recent volumes that have attempted to provide summaries of these fields have been, in actuality, transcripts of symposia. Despite the pains of the editors, these tomes suffer from a lack of continuity of styl...
متن کاملThe chemistry of the antibody molecule.
Immunochemistry has traditionally focused on understanding the molecular basis of antibody binding affinity and specificity. In the last 20 years a major shift has occurred in the field. We are now asking how we can exploit the remarkable properties of the antibody molecule and the immune response in chemistry-from testing basic theories of enzymatic catalysis to the synthesis of new catalysts....
متن کاملProduction of a monoclonal antibody against chicken immunoglobulin G: A valuable molecule with research and diagnostic applications
Monoclonal antibodies (MAbs) are invaluable molecules which have several advantages over polyclonal immunoglobulins (Igs) including consistency and higher specificity and hence can be used in biological researches, diagnosis and treatment of diseases. The present study was conducted to produce monoclonal antibody against chicken IgG.TheIgG molecules were purified from chicken serum and used as ...
متن کاملRe: bispecific small molecule-antibody conjugate targeting prostate cancer.
Bispecific antibodies, which simultaneously target CD3 on T cells and tumor-associated antigens to recruit cytotoxic T cells to cancer cells, are a promising new approach to the treatment of hormone-refractory prostate cancer. Here we report a site-specific, semisynthetic method for the production of bispecific antibody-like therapeutics in which a derivative of the prostate-specific membrane a...
متن کاملGeneration of monoclonal antibody against canine neural-cell adhesion molecule.
A monoclonal antibody, K9BYU, was generated using Escherichia coli recombinant extracellular domain of canine neural-cell adhesion molecule (N-CAM) as an antigen. Immunoreactivity of K9BYU to insect cell recombinant canine N-CAM was demonstrated by Western blotting using Sf9 insect cells transfected with the canine N-CAM gene. In Western blotting against canine brain tissue, K9BYU detected thre...
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ژورنال
عنوان ژورنال: Nature
سال: 1975
ISSN: 0028-0836,1476-4687
DOI: 10.1038/258177a0